Genetics of Original Sin The Impact of Natural Selection on the Future of Humanity Christian De Duve, Neil Patterson, Edward O. Wilson

Increasingly absorbed in recent years by advances in our understanding of the origin of life, evolutionary history, and the advent of humankind, eminent biologist Christian de Duve of late has also pondered deeply the future of life on this planet. He speaks to readers with or without a scientific background, offering new perspectives on the threat posed by humanity's immense biological success and on the resources human beings have for altering their current destructive path.

Focusing on the process of natural selection, de Duve explores the inordinate and now dangerous rise of humankind. His explanation for this self-defeating success lies in the process of natural selection, which favours traits that are immediately useful, regardless of later consequences. Thus, the human genome determines such properties as tribal and group cohesion and collaboration and often fierce and irrational competition with and hostility toward other groups' attributes that were once useful but now often ruinously dysfunctional. Christian de Duve suggests that these traits, imprinted into human nature by natural selection, may have been recognized by the writers of Genesis, thus inspiring the myth of original sin.

Is there redemption for genetic original sin? In a brilliant and original conclusion, the author argues that, unique in the living world, humankind is endowed with the ability to deliberately oppose natural selection. Human beings have the capacity to devise measures that, while contrary to local or personal interests, can bring forth a safer world.

Christian de Duve is professor emeritus at the Catholic University of Louvain, Belgium, and at Rockefeller University, New York. During his distinguished career he has received numerous honours and prizes, including the 1974 Nobel Prize in Physiology or Medicine and fifteen honorary degrees. He lives in Belgium.

"Alone on planet Earth, humans have come to understand the mechanism of their biological legacy, and to devise ways to transcend it. No better account can be found of the stark choices that humanity now faces, and no more authoritative a guide and expositor than Christian de Duve."—Paul Davies, author of The Eerie Silence